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Illicit drug use costs the United States approximately $181 billion every year.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Egg cells are about the size of a grain of sand. They are formed inside of a female's ovaries before she is even born.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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