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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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Colchicine is a highly poisonous alkaloid originally extracted from a type of saffron plant that is used mainly to treat gout.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.