Which electrophile will react the fastest by the SN2 mechanism ...

[robinn137]

Which electrophile will react the fastest by the SN2 mechanism with cyanide (NC) in DMF?
  1.phenyl iodide (PhI)
  2.vinyl tosylate (H2C=CHOTos)
  3.ethyl bromide
  4.cyclohexyl bromide
  5.benzyl tosylate (Ph-CH2-OTos)

Question 2

Select the substrate which would react fastest in the substitution reaction.
 

Question 3

What statement about the S_N2 reaction of methyl bromide with hydroxide is incorrect?
  1.The reaction kinetics is first-order in hydroxide.
  2.In the transition state the carbon is sp2 hybridized.
  3.Absolute configuration is inverted from R to S.
  4.The reaction is faster in HMPA than in water.
  5.The reaction can be catalyzed by I.

[Brummell1998]

Answer to Question 1

5

Answer to Question 2

1

Answer to Question 3

3