Author Question: Instructions: Refer to the data below to answer the following question(s). Porcine dynorphin is ... (Read 61 times)

natalie2426

  • Hero Member
  • *****
  • Posts: 524

Instructions: Refer to the data below to answer the following question(s).
 
   Porcine dynorphin is a neuropeptide having 17 amino acid residues. Its structure is shown below.
 
   TyrGlyGlyPheLeuArgA rgIleArgProLysLeuLy sTrpAspAsnGln


  Refer to instructions. What fragments would result if dynorphin were cleaved by trypsin?

Question 2

Draw the structure of the product of the following reaction and describe the usefulness of this type of reaction.
 
   



Question 3

Write the equation for the reaction, using methanol (CH3OH), that would render the carboxyl group of alanine unreactive.

Question 4

Draw and name the structure of the product of the following reaction.
 
   



Question 5

Instructions: Consider the following structure. Based on this structure answer the following question(s).
 
   


  Refer to instructions. How many other peptides could be formed from this same combination of amino acids?
   
  a.
  3
   
  b.
  6
   
  c.
  9
   
  d.
  12

Question 6

Instructions: Consider the following structure. Based on this structure answer the following question(s).
 
   


  Refer to instructions. Name the peptide using both the three-letter and one-letter codes.

Question 7

Instructions: Consider the following structure. Based on this structure answer the following question(s).
 
   


  Refer to instructions. Circle the peptide bonds.

Question 8

Instructions: Consider the following structure. Based on this structure answer the following question(s).
 
   


  Refer to instructions. Identify the C-terminal amino acid and the N-terminal amino acid.

Question 9

Instructions: Refer to the data below to answer the following question(s).
 
   Leucine is an essential amino acid with the systematic name 2-amino-3-methylpentanoic acid. It has pKa1 = 2.36 and pKa2 = 9.60.


  Refer to instructions. Leucine is described as an essential amino acid. What does this mean?



johnharpe

  • Sr. Member
  • ****
  • Posts: 338
Answer to Question 1

Trypsin catalyzes the hydrolysis of peptides as the carboxyl side of arginine and lysine. Consequently, the fragments resulting from trypsin hydrolysis of dynorphin are:



TyrGlyGlyPheLeuArg

Arg

IleArg

ProLys

LeuLys

TrpAspAsnGln

Answer to Question 2


Removal of a protecting group that was added to the carboxyl group. Often used in protein synthesis

Answer to Question 3



Answer to Question 4



Answer to Question 5

b

Answer to Question 6

SerPheGly

SFG



Answer to Question 7



Answer to Question 8



Answer to Question 9

Humans are able to synthesize only 10 of the 20 amino acids necessary for protein synthesis. The remaining 10 are called essential amino acids since they must be obtained from dietary sources. Failure to include an adequate dietary supply of these essential amino acids can lead to severe deficiency diseases.



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
 

Did you know?

The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.

Did you know?

The immune system needs 9.5 hours of sleep in total darkness to recharge completely.

Did you know?

Barbituric acid, the base material of barbiturates, was first synthesized in 1863 by Adolph von Bayer. His company later went on to synthesize aspirin for the first time, and Bayer aspirin is still a popular brand today.

Did you know?

Many medications that are used to treat infertility are injected subcutaneously. This is easy to do using the anterior abdomen as the site of injection but avoiding the area directly around the belly button.

Did you know?

A serious new warning has been established for pregnant women against taking ACE inhibitors during pregnancy. In the study, the risk of major birth defects in children whose mothers took ACE inhibitors during the first trimester was nearly three times higher than in children whose mothers didn't take ACE inhibitors. Physicians can prescribe alternative medications for pregnant women who have symptoms of high blood pressure.

For a complete list of videos, visit our video library