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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
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The immune system needs 9.5 hours of sleep in total darkness to recharge completely.
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The average adult has about 21 square feet of skin.
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More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.