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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.
During pregnancy, a woman is more likely to experience bleeding gums and nosebleeds caused by hormonal changes that increase blood flow to the mouth and nose.
The longest a person has survived after a heart transplant is 24 years.