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To combat osteoporosis, changes in lifestyle and diet are recommended. At-risk patients should include 1,200 to 1,500 mg of calcium daily either via dietary means or with supplements.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.