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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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Excessive alcohol use costs the country approximately $235 billion every year.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Everyone has one nostril that is larger than the other.