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ACTH levels are normally highest in the early morning (between 6 and 8 A.M.) and lowest in the evening (between 6 and 11 P.M.). Therefore, a doctor who suspects abnormal levels looks for low ACTH in the morning and high ACTH in the evening.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.