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Asthma is the most common chronic childhood disease in the world. Most children who develop asthma have symptoms before they are 5 years old.
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Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.