Author Question: A highly lipid-soluble drug a. Is unable pass through the blood-brain barrier. b. Must be ... (Read 57 times)

EAugust · **on:** Jun 22, 2018

A highly lipid-soluble drug

a. Is unable pass through the blood-brain barrier.
b. Must be converted by cytochrome P450 enzymes to a water-soluble
from before being capable of penetrating the blood-brain barrier.
c. Should be capable of entering the brain.
d. Is unlikely to have any relevant biological effects.

Question 2

Sensitization occurs when

a. Increasingly higher doses of a drug are needed to produce the desired
effect.
b. Tolerance occurs.
c. The same dose of a drug produces a greater effect.
d. The therapeutic index increases.