Physical dependence associated with down-regulation of receptors ...

[evelyn o bentley]

Physical dependence associated with down-regulation of receptors is most likely to occur with drugs that
 
  a. deplete neurotransmitters
  b. reduce receptor activation
  c. increase receptor activation
  d. enhance hepatic enzyme production

Question 2

What technique is most commonly used with nonhumans to determine whether or not a drug has dependence liability?
 
  a. determine if the drug disrupts instrumental behavior
  b. determine if they will self-administer the drug
  c. determine if the drug has a low therapeutic index
  d. determine if tolerance occurs to the drug with repeated exposures

[anyusername12131]

Answer to Question 1

c

Answer to Question 2

b