Author Question: An action potential arrives at an axon terminal. Describe the general process of synaptic ... (Read 51 times)

amal · **on:** Jun 22, 2018

An action potential arrives at an axon terminal. Describe the general process of synaptic neurotransmission from that point on with respect to presynaptic and postsynaptic activity in the synapse.

What will be an ideal response?

Question 2

When one is concerned with a drug's pharmacokinetics, one is chiefly concerned with

a. the behavioral effects of the drug
b. the mechanism of action of the drug
c. the long term consequences of exposure to the drug
d. the processes involved in the absorption, metabolization, and excretion of the drug

kxciann · **Reply #1 on:** Jun 22, 2018

Answer to Question 1

Ca++ entry into terminal causes release of neurotransmitter (NT) molecules, primarily from vesicles, into cleft. NT passively diffuses across cleft and binds to post-synaptic receptors to induce either IPSP or EPSP, depending upon the type of ion flow into or out of post-synaptic neuron. The NT then dissociates from the receptors and may undergo reuptake back into the axon terminal or nearby glial cells, be enzymatically inactivated, or diffuse throughout the extracellular fluid.

Answer to Question 2

d