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About 3.2 billion people, nearly half the world population, are at risk for malaria. In 2015, there are about 214 million malaria cases and an estimated 438,000 malaria deaths.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
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Asthma cases in Americans are about 75% higher today than they were in 1980.