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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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The average adult has about 21 square feet of skin.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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The lipid bilayer is made of phospholipids. They are arranged in a double layer because one of their ends is attracted to water while the other is repelled by water.