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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.
The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.