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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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The FDA recognizes 118 routes of administration.
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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.