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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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The longest a person has survived after a heart transplant is 24 years.