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By definition, when a medication is administered intravenously, its bioavailability is 100%.
More than 30% of American adults, and about 12% of children utilize health care approaches that were developed outside of conventional medicine.
It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
The human body produces and destroys 15 million blood cells every second.
In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.