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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Excessive alcohol use costs the country approximately $235 billion every year.
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
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Vaccines prevent between 2.5 and 4 million deaths every year.
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The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.