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The familiar sounds of your heart are made by the heart's valves as they open and close.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Pubic lice (crabs) are usually spread through sexual contact. You cannot catch them by using a public toilet.
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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.