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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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A good example of polar molecules can be understood when trying to make a cake. If water and oil are required, they will not mix together. If you put them into a measuring cup, the oil will rise to the top while the water remains on the bottom.
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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.