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Elderly adults are at greatest risk of stroke and myocardial infarction and have the most to gain from prophylaxis. Patients ages 60 to 80 years with blood pressures above 160/90 mm Hg should benefit from antihypertensive treatment.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Earwax has antimicrobial properties that reduce the viability of bacteria and fungus in the human ear.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.