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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
A strange skin disease referred to as Morgellons has occurred in the southern United States and in California. Symptoms include slowly healing sores, joint pain, persistent fatigue, and a sensation of things crawling through the skin. Another symptom is strange-looking, threadlike extrusions coming out of the skin.
Asthma cases in Americans are about 75% higher today than they were in 1980.
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
In 1864, the first barbiturate (barbituric acid) was synthesized.