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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
Once thought to have neurofibromatosis, Joseph Merrick (also known as "the elephant man") is now, in retrospect, thought by clinical experts to have had Proteus syndrome. This endocrine disease causes continued and abnormal growth of the bones, muscles, skin, and so on and can become completely debilitating with severe deformities occurring anywhere on the body.
In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.