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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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More than 34,000 trademarked medication names and more than 10,000 generic medication names are in use in the United States.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.