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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
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The first-known contraceptive was crocodile dung, used in Egypt in 2000 BC. Condoms were also reportedly used, made of animal bladders or intestines.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The first oncogene was discovered in 1970 and was termed SRC (pronounced "SARK").