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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.