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In 1864, the first barbiturate (barbituric acid) was synthesized.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.
In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.
The newest statin drug, rosuvastatin, has been called a superstatin because it appears to reduce LDL cholesterol to a greater degree than the other approved statin drugs.