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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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The first monoclonal antibodies were made exclusively from mouse cells. Some are now fully human, which means they are likely to be safer and may be more effective than older monoclonal antibodies.
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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%