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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.
There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
Never take aspirin without food because it is likely to irritate your stomach. Never give aspirin to children under age 12. Overdoses of aspirin have the potential to cause deafness.