Question 1
You identify a cell in which DNA polymerase III is functional, but it seems to exhibit extremely low processivity. This is likely a defect in what structure?
◦ the t proteins
◦ the pol III holoenzyme
◦ the clamp loader
◦ the topoisomerase enzyme
◦ the sliding clamp
Question 2
During DNA replication in
E. coli, how does the cell prevent the DNA strands from following their natural tendency to seek maximum stability and reanneal?