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Author Question: Why are eukaryotic mRNAs not polycistronic, unlike some bacterial transcripts? (Read 58 times)

rosent76

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on: Jan 12, 2022
Why are eukaryotic mRNAs not polycistronic, unlike some bacterial transcripts?
◦ Eukaryote's genetic code is non-overlapping, and so coding sequences cannot overlap on the same mRNA.
◦ Eukaryotes have more complex translational machinery than bacteria that is also less efficient in initiating translation.
◦ Eukaryotic mRNAs are generally shorter than bacteria mRNAs, and so do not contain sufficient information to encode additional polypeptides.
◦ Bacteria couple their translation with transcription, while eukaryotes do not.
◦ The eukaryotic ribosome must bind to the 5' end of the mRNA and scan, while the bacterial ribosome can bind to a Shine-Delgarno sequence anywhere in the mRNA.
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Marked as best answer by rosent76 on Jan 12, 2022

brittiany.barnes

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Reply #1 on: Jan 12, 2022
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rosent76

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Reply 2 on: Jan 12, 2022
Excellent

ttt030911

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Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

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