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Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
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The strongest synthetic topical retinoid drug available, tazarotene, is used to treat sun-damaged skin, acne, and psoriasis.
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Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.

