Modification of activity of some promoters by methylation is due to:
◦ changes in conformation of the template that only prevent transcription factor binding.
◦ changes in conformation of the template that only stimulate transcription factor binding.
◦ only repressor proteins binding specifically to methylated promoter sites.
◦ changes in conformation of the template that either prevent or stimulate transcription factor binding.
◦ changes in conformation of the template that either prevent transcription factor binding or stimulate repressor proteins binding.