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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.
In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
If all the neurons in the human body were lined up, they would stretch more than 600 miles.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.