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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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There are more bacteria in your mouth than there are people in the world.
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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Asthma cases in Americans are about 75% higher today than they were in 1980.
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Increased intake of vitamin D has been shown to reduce fractures up to 25% in older people.