Author Question: Which of the following drugs is the angiotensin-converting enzyme (ACE) inhibitor of choice for ... (Read 89 times)

daltonest1984 · **on:** Jul 23, 2018

Which of the following drugs is the angiotensin-converting enzyme (ACE) inhibitor of choice for slowing progression of chronic renal failure (CRF) to end-stage renal disease (ESRD)?

a. Captopril (Capoten)
b. Benazepril (Lotensin)
c. Enalapril (Vasotec)
d. Lisinopril (Prinivil)

Question 2

Which of the following medications, if crushed, may have teratogenic effects in a male fetus if the patient's female sex partner is exposed to it?

a. Dutasteride
b. Finasteride
c. Doxazosin
d. Prazosin

jharrington11 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: A
The most commonly used ACE inhibitor approved by the Food and Drug Administration (FDA) for management of patients with CRF or ESRD is captopril. It blocks the conversion of angio-tensin I to angiotensin II, which reduces efferent arteriolar vasoconstriction and normalizes blood pressure.

Answer to Question 2

ANS: B
Advise the male patient not to expose a female sex partner to a crushed table of finasteride be-cause of the potential for teratogenic effects in a male fetus.