A nursing student asks the nurse what differentiates antiestrogen ...

[sam.t96]

A nursing student asks the nurse what differentiates antiestrogen drugs from aromatase inhibitors in the treatment of breast cancer. What is the correct response by the nurse?
 
  a. Antiestrogen drugs decrease the risk for thromboembolic events.
  b. Antiestrogen drugs increase the risk for endometrial cancer.
  c. Aromatase inhibitors block the production of estrogen by the ovaries.
  d. Aromatase inhibitors can be used for tumor cells that lack estrogen receptors.

Question 2

The nurse on an oncology unit prepares to administer the fourth cycle of docetaxel (Taxotere) to a patient with breast cancer. Which clinical finding would cause the nurse to withhold the dose and call the prescriber?
 
  a. Neutrophil count of 2000/mm3
  b. Neutrophil count of 1700/mm3
  c. Neutrophil count below 1500/mm3
  d. Creatinine clearance of 130 mL/min/1.73 m2

[harveenkau8139]

Answer to Question 1

ANS: B
Antiestrogen drugs cause proliferation of endometrial tissue by acting as receptor agonists at receptors in the uterus. Antiestrogen drugs increase the risk of thromboembolic events. Aromatase inhibitors block the production of estrogen from androgenic precursors, not by the ovaries. Aromatase inhibitors are used to treat ER-positive breast cancer.

Answer to Question 2

ANS: C
If the neutrophil count drops below 1500/mm3, the nurse should withhold the dose and notify the prescriber. The other values do not indicate a need to withhold the dose.

[sam.t96]

TY

[harveenkau8139]

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