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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.