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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
To combat osteoporosis, changes in lifestyle and diet are recommended. At-risk patients should include 1,200 to 1,500 mg of calcium daily either via dietary means or with supplements.
Approximately 500,000 babies are born each year in the United States to teenage mothers.
More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.