Answer to Question 1
ANS: D
Though associated with various side effects, including digestive disturbance, 5-azacytidine has shown promise in the treatment of pancreatic cancer. There is no support for its use in the treat-ment of liver, colon, or gallbladder cancers.
Answer to Question 2
ANS: C
Conditions encountered in utero, during childhood, and even during adolescence or later can have long-term impacts on epigenetic states, which sometimes can be transmitted across genera-tions. The impact is not supported for the periods of infancy, puberty, and middle age.