Which of the following mutations have the most significant effect ...

[vinney12]

Which of the following mutations have the most significant effect on protein synthesis?
 
  a. Base pair substitutions
  b. Silent mutations
  c. Intron mutations
  d. Frameshift mutations

Question 2

A DNA strand has a region with the sequence ATCGGAT. Which of the following would be a complementary strand?
 
  a. CGATACGT
  b. TAGCCTAG
  c. TUGCCTUG
  d. UAGCCUAG

[vkodali]

Answer to Question 1

ANS: D
The frameshift mutation involves the insertion or deletion of one or more base pairs of the DNA molecule. This greatly alters the amino acid sequence, which affects protein synthesis. The base pair substitution is a type of mutation in which one base pair replaces another. Silent mutations do not change amino acids or protein synthesis. Intron mutations are part of RNA sequencing.

Answer to Question 2

ANS: B
The consistent pairing of adenine with thymine and of guanine with cytosine is known as com-plementary base pairing; thus, A complements to T and C to G and vice versa throughout the strand. A complements to T; thus, the first letter must be a T. U does not represent a complement in the sequence.