Of the following patient conditions, which patients would be at ...

[darbym82]

Of the following patient conditions, which patients would be at risk for experiencing a thyroid problem due to a decrease in thyroxine-binding globulin (TBG)? Select all that apply.
 
  A)
  A 55-year-old male with cirrhosis due to alcohol abuse
  B)
  A 47-year-old female experiencing hot flashes and excess diaphoresis related to menopause
  C)
  A 75-year-old man receiving chronic glucocorticoid therapy to treat his severe chronic obstructive pulmonary disease (COPD)
  D)
  A 18-year-old female anorexia nervosa patient weighing 78 lb and has consumed no protein for the past 3 years

Question 2

A 20-year-old male college student has recently finished a Thanksgiving dinner of heroic proportions while home for the holiday weekend. Which of the following phenomena would most likely have produced his sensation of satiety?
 
  A)
  Stretch receptors in the stomach and small intestine signal the feeding center in the medulla.
  B)
  Increased levels of leptin stimulate a decrease in appetite by way of the vagus nerve.
  C)
  The breakdown of products of lipids such as ketoacids produces a decrease in appetite.
  D)
  Cholecystokinin and glucagon-like peptide-1 suppress the hunger impulse.

[Yixagurpuldink]

Answer to Question 1

Ans:
A, C, D

Feedback:

A number of disease conditions and pharmacologic agents can decrease the amount of binding protein in the plasma or influence the binding of hormone. Glucocorticoid medications and systemic disease conditions such as protein malnutrition, nephritic syndrome, and cirrhosis decrease TBG concentrations.

Answer to Question 2

Ans:
D

Feedback:

The presence of fat in the duodenum and nutrients in the small bowel results in the release of cholecystokinin and glucagon-like peptide-1, respectively, which suppress the feeding center located in the hypothalamus. Leptin and ketoacids are associated with the intermediate and long-term regulation of food intake rather than the short-term control that would signal the end of a meal or snack.

[darbym82]

Excellent

[Kedrick2014]

TYSM