A progressive systemic skeletal disease characterized by low bone mass and micro architectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptible to fracture describes which of the following diseases?
A. Osteosarcoma
B. Osteoporosis
C. Renal osteodystrophy
D. Paget's disease
Question 2
Which of the following laboratory results best represents a patient with Paget's disease?
A. Decreased urinary hydroxyproline, increased serum alkaline phosphatase
B. Increased urinary hydroxyproline, decreased serum alkaline phosphatase
C. Normal urinary hydroxyproline, normal serum alkaline phosphatase
D. Decreased urinary hydroxyproline, decreased serum alkaline phosphatase
ossification of bone
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