Author Question: Chronic kidney disease is defined by the Kidney Disease Outcomes Quality Initiative of the National ... (Read 123 times)

Caiter2013 · **on:** Jun 25, 2018

Chronic kidney disease is defined by the Kidney Disease Outcomes Quality Initiative of the National Kidney Foundation as a:

A) glomerular filtration rate of less than 60 mL/min for 3 months or more.
B) glomerular filtration rate of less than 100 mL/min for 3 months or more.
C) glomerular filtration rate of less than 40 mL/min for 6 months or more.
D) glomerular filtration rate of less than 120 mL/min for 3 months or more.

Question 2

A laboratory staff member is interested in evaluating a new technology (Optode) for measuring potassium in serum. The technologist performs a split sample study by measuring potassium using their current method, ISE, and the new method.

Determine the slope and intercept using a linear regression by least-squares analysis. Also calculate the Pearson product-moment correlation coefficient.
Which of the following responses reflects the correct values for each calculated parameter?

Sample Potassium (ISE) reference method (meq/L) - x-axis Potassium (Optode) new method (meq/L) - y-axis
1 4.5 4.7
2 2.4 2.7
3 7.4 7.6
4 10.1 10.2
5 6.1 6.2
6 12.4 12.3
7 6.1 6.2
8 10.0 10.2
9 7.2 7.1
10 8.1 8.2
11 3.6 3.8
12 8.4 8.4
13 4.4 4.7
14 8.6 8.7
15 8.1 8.4
16 11.3 11.4
17 8.3 8.2
18 9.0 9.2
19 5.8 6.0
20 3.5 3.7
21 3.0 3.1
22 4.0 4.0
23 4.5 4.6
24 2.5 3.0
25 7.0 7.0

A) Slope: 1.02, intercept: -0.283, correlation coefficient: 0.998
B) Slope: 0.976, intercept: 0.290, correlation coefficient: 0.998
C) Slope: 0.976, intercept: -0.283, correlation coefficient: 0.998
D) Slope: 1.02, intercept: 0.290, correlation coefficient: 0.998