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Author Question: Which of the following is the most important protease of the coagulation pathway because of its role ... (Read 20 times)

CQXA

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on: Jun 25, 2018
Which of the following is the most important protease of the coagulation pathway because of its role in so many different catalytic functions?
 
  a. Thrombin
  b. Factor XIa
  c. Plasmin
  d. Factor VIIa

Question 2

Oral anticoagulation is based on:
 
  a. Increasing plasminogen
  b. Activating plasmin
  c. Combining with antithrombin
  d. Vitamin K antagonism


chloejackso

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Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: A
Thrombin is considered the most important protease of the coagulation pathway because of its multiple functions. These include splitting fibrinogen to form fibrin monomers; activating the cofactors V and VIII; activating factor XIII; binding to thrombomodulin to activate protein C; and aggregating platelets, to name just a few.

Answer to Question 2

ANS: D
Vitamin K antagonism is the basis for oral anticoagulation.


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