Which of the following is a common feature of the myelodysplastic ...

[mcmcdaniel]

Which of the following is a common feature of the myelodysplastic syndromes?
 
  a. Peripheral blasts between 5 and 20
  b. Progressive cytopenias and dyspoiesis in one or more cell lines
  c. Macrocytic red cells and leukocytosis
  d. Low mean cell volume (MCV) and thrombocytopenia

Question 2

Which of the following is true for chronic myelogenous leukemia?
 
  a. It is a clonal process arising from the pluripotent stem cell.
  b. It is most commonly found in children 5 to 10 years old.
  c. Common symptoms include an elevated red cell mass.
  d. Lymphadenopathy is common.

[Expo]

Answer to Question 1

ANS: B
Progressive cytopenias and dyspoiesis in one or more cell lines is characteristic of myelodysplastic syndromes. Although blasts may be increased in the peripheral blood, they are generally less than 5. Macrocytic red cells may be present so that the MCV may be elevated; however, the white count is usually normal or decreased (depends on type), and platelets are normal to decreased.

Answer to Question 2

ANS: A
Chronic myelogenous leukemia is a clonal process arising from the pluripotent stem cell. It is most commonly found in middle-aged adults. A mild anemia that progresses is common, not an elevated red cell mass; enlarged lymph nodes are not characteristic.

[mcmcdaniel]

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