Author Question: Moderate to marked target cells are found on a blood film. Which of the following can most likely be ... (Read 105 times)

SO00

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Moderate to marked target cells are found on a blood film. Which of the following can most likely be eliminated
 
  a. Hb C disease
  b. Hereditary spherocytosis
  c. Hb E disease
  d. Sickle cell disease

Question 2

Select the best test to confirm the diagnosis of the patient in Question 9.
 
  a. Mean cell volume (MCV)
  b. Osmotic fragility
  c. Hemoglobin electrophoresis
  d. Presence of sickle cells



jjorrostieta

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Answer to Question 1

ANS: B
Target cells are not seen in hereditary spherocytosis. They are present in all the other conditions listed.

Answer to Question 2

ANS: C
The best test to differentiate sickle cell trait from anemia is hemoglobin electrophoresis. Sickle cell trait should have roughly 40 Hb S and 55 Hb A, whereas sickle cell anemia should have predominantly Hb S with a variably increased Hb F and no Hb A.



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