Author Question: Which of the following conditions is associated with a deficiency of von Willebrand factor ... (Read 22 times)

kfurse · **on:** Jun 25, 2018

Which of the following conditions is associated with a deficiency of von Willebrand factor (VWF)-cleaving protease?

a. Hemolytic uremic syndrome
b. Thrombotic thrombocytopenic purpura
c. March hemoglobinuria
d. DIC

Question 2

An Rh-negative woman is pregnant with her third child. She received little or no prenatal care during the first two pregnancies. Her anti-D titer is 1:512 at 30 weeks of gestation. What is the likely outcome for the baby?

a. ABO hemolytic disease of the newborn
b. Rh hemolytic disease of the newborn
c. No or mild hemolysis but spherocytes on the blood film
d. Most likely not survive

lorealeza77 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

ANS: B
A severe deficiency of VWF-cleaving protease has been described in patients with thrombotic thrombocytopenic purpura.

Answer to Question 2

ANS: B
This baby will most likely have Rh hemolytic disease of the newborn. The mother's antibody titer does not predict the severity of hemolytic disease of the newborn.